SUPPLEMENT
ANALYSIS
21st Century Prolonged Release Niacin 250 mg
AI-Powered Safety Report · SafeShelf
⚕️ Data Aggregation & Medical Disclaimer
SafeShelf is a technology platform, not a medical provider. This analysis is generated by an AI system that aggregates public regulatory data (such as EU and FDA databases) and is provided for educational and informational purposes only. It is not medical advice, a clinical diagnosis, or a substitute for professional healthcare guidance. SafeShelf has no doctors on staff and cannot guarantee the accuracy of AI-generated assessments.
Do not make health, dietary, or medical decisions based solely on this report. Always consult a qualified healthcare professional — especially if you have a medical condition, are pregnant, take prescription medications, or are acting on behalf of an infant or child.
Do not make health, dietary, or medical decisions based solely on this report. Always consult a qualified healthcare professional — especially if you have a medical condition, are pregnant, take prescription medications, or are acting on behalf of an infant or child.
75
Good
21st Century Prolonged Release Niacin 250 mg
niacin vitamin supplement
high confidence
This is a 250 mg prolonged-release niacin supplement intended for energy and circulatory support. While niacin is a vital B-vitamin, the 250 mg dose significantly exceeds the recommended daily allowance and carries a risk of 'niacin flush' and potential interactions with certain medications.
📊 Score Breakdown
Drug Interaction Risk
30% of overall
60
Niacin can interact with statins, blood pressure medications, and diabetes medications by altering blood sugar or lipid profiles.
Megadose Toxicity
25% of overall
50
250 mg is well above the 35 mg Tolerable Upper Intake Level (UL) for niacin, increasing the risk of flushing and gastrointestinal discomfort.
Bioavailability Quality
20% of overall
90
Prolonged-release formulations are designed to mitigate the intensity of the niacin flush effect.
Filler Quality
15% of overall
85
Standard excipients used in tablet manufacturing; no high-risk artificial dyes or problematic fillers identified.
Label Transparency
10% of overall
90
Clear dosage and product purpose provided.
🚨 Critical Warnings
Consult a physician before use if you are taking statins, blood pressure medication, or have a history of liver disease or gout.
Niacin can cause a harmless but uncomfortable 'flush' (redness, itching, or tingling of the skin) in some individuals.
✅ What's Good
- ✓Supports energy metabolism and circulatory health
- ✓Prolonged-release formula helps reduce the incidence of niacin flush
⚠️ Flagged Ingredients
Niacin (250 mg)
MEDIUM
Dose exceeds the 35 mg UL; may cause flushing, liver enzyme elevation, or blood sugar fluctuations.
🔬 Full Ingredient Breakdown
Every identified ingredient classified by safety level.
Niacin
moderate
💡 Recommendations
- →Start with a lower dose or take with food to minimize potential flushing.
- →Monitor for signs of liver stress (e.g., jaundice, dark urine) if taking high doses long-term.
- →Do not exceed the recommended dose without medical supervision.
⚕️ Reminder: This AI report is for informational purposes only and does not replace
professional medical advice. Ingredient safety can vary based on individual health factors, dosage,
product formulation, and applicable regulations in your country. SafeShelf assumes no liability for
decisions made based on this analysis.